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2017, Xyzal Allergy 24HR allergy relief became available as an OTC product. The “24 hour relief” part of Xyzal Allergy 24HR applies to the prescription product, as well. XYZAL starts working one hour after taking the medication. † So, when looking for a smaller tablet, consider Xyzal Xyzal ( levocetirizine) and Zyrtec ( cetirizine) are both antihistamines. (desloratadine), or Xyzal (levocetirizine) Go OTC Alavert, Claritin (or generic loratadine), or Zyrtec (cetirizine) Save as much as 8 a month*. In this article, we will discuss everything you want to know about Xyzal OTC! Follow all directions on your prescription label and read all medication guides or instruction sheets. Store brands for OTC levocetirizine are also available Take Xyzal exactly as prescribed by your doctor. Yes, XYZAL Allergy 24HR is the same original, full prescription strength medicine as XYZAL. Over-the-counter vs Prescription Xyzal (Levocetirizine) Until 2017, levocetirizine tablets were available in the US only by prescription from a doctor. Xyzal Allergy 24HR, from Sanofi, contains levocetirizine, an antihistamine previously only available with a prescription. Xyzal is produced by Sanofi, and Zyrtec is produced by a division of Johnson & Johnson. The recommended dosage for adults and children ages 12 and up is one 5 mg tablet per day Xyzal(levocetirizine) Enter another drug to compare Prescription and OTC Prescribed for Urticaria, Allergic Rhinitis, Allergies. The main difference between the two products is in the size of pill; Xyzal pills are nearly half the size as Zyrtec pills. Xyzal was initially approved in 2007 by the FDA as a prescription only medication indicated for the treatment of seasonal and year round allergy symptoms. Both come as tablets with 5 mg of levocetirizine each. XYZAL tablets are available in 10 count, 35 count, 55 count, 80 count and 110 — (110 count is only available at club stores) Xyzal vs Zyrtec ® On first dose, Xyzal provides the same relief as Zyrtec. Levocetirizine may also be used for purposes not listed in this medication guide. They’re both marketed as providing. Prescription only Prescribed for Urticaria, Allergic Rhinitis, Allergies.. Use the medicine exactly as directed. OTC Xyzal Allergy 24HR is the same strength as the prescription product. Follow your doctor's dosing instructions very carefully Overview Xyzal (Levocetirizine) is an allergy medication that is available over the counter beginning Spring 2017. How quickly does XYZAL start working? A child's dose of levocetirizine is based on the age of the child. It is available in the same strengths and dosage forms as prescription Xyzal. In January 2017, the FDA deregulated levocetirizine and allowed it for sale without a prescription (over-the-counter) Prescription medication is not always the best. What sizes of XYZAL are available?